WHO provides the government of Uganda technical assistance for management of national health programmes (primary health care, malaria, tuberculosis, AIDS, onchocerciasis, epidemiological surveillance, control and elimination of specific community diseases). Technical assistance has taken the form of training, consultants, equipment, and vehicles. In some situations WHO provides drugs.

In 1987, WHO supported the government of Uganda through the Ministry of Health to establish the STD/AIDS Control Programme which has waged a relentless campaign against HIV/AIDS. Assistance has ranged from technical, material and financial support to surveillance; and Information, Education and Communication (IEC) activities.